August 2, 2022
Surgical Adhesives That Bond at Body Temperature
Bio-reactive HMAs melt at 50°C (near body temperature) and bond tissue within seconds. Key features:
Star-polycaprolactone (PCL-NHS) base: Biodegrades in weeks without toxic residues.
4x stronger than surgical sutures: Withstands internal fluid exposure and dynamic movement.
Used for minimally invasive wound closure and organ repair.
Skin-Friendly HMAs for Wearable Medical Devices
Pressure-sensitive HMAs (PSAs) enable comfortable long-term wear for:
Glucose monitors: Adhere through sweat and movement, with hypoallergenic properties.
ECG electrodes: Maintain conductivity without skin irritation.
These pass cytotoxicity tests (ISO 10993-5) and offer breathable adhesion.
Drug-Delivery Patches with Smart Adhesion
HMAs with controlled porosity act as drug reservoirs in transdermal patches:
Thermo-responsive release: Drugs diffuse when skin temperature rises.
Biodegradable backing: Reduces medical waste.